About us

From fecal transplantation to washed microbiota transplantation

We strive to establish the foremost microbial therapy system in the world. As a leading center for microbiota medicine, we offer nationwide nonprofit remote rescue services for washed microbiota transplantation to all hospitals, providing medical services to patients who travel from around the globe to Nanjing.

Our rescue in China and services for patients around the world

In 2015, Professor Faming Zhang, Daiming Fan and Kaichun Wu jointly initiated the Chinese fmtBank emergency rescue plan, which is a non-profit organization. We developed the first automatic microbiota purification system GenFMTer (FMT Medical, Nanjing, China) in the world, established the first two GMP-level laboratories (biosafety level 3) for washed microbiota transplantation, and developed the China Microbiota Transplantation System (CMTS) for long-term evaluation for microbiota transplantation. Our official website is fmtbank.org for providing national non-profit service and research.

More than 60% of patients underwent fecal microbiota transplantation (FMT)were from our group.Our clinical rescue for patients with refractory intestinal infections are distributed whole China, as far as Dalian in the east, Sanya in the south, Yili in the west, and Mohe in the north. We adopted cases from China, Japan, Europe, Australia, England and the United States.

In 2019, we and our collaborators in China mainland and China Taiwan are stepping into the era of washed microbiota transplantation (WMT).

Our Team Progress

●Dr. Faming Zhang defined the medical history of FMT in “American Journal of Gastroenterology”, and coined the Chinese name of ``fecal microbiota transplantation`` in CHINA JOURNAL OF ENDOSCOPY; The first clinical trial of FMT in China was registered by us.

● We reported the first FMT in case with severe fistulizing Crohn's disease. We launched the non-profit research fund Intestine Initiative.

●We invented the first automatic microbiota purification system GenFMTer (FMT Medical, Nanjing, China); Sponsored the 1st National Conference on Intestinal Disease and Fecal Microbiota Transplantation. Dr. Bota Cui et al. reported that FMT is effective in treating Crohn's disease-related abdominal pain, as well as other findings; Faming Zhang conceived and started to study Cap-assisted Endoscopic Sclerotherapy (CAES) for hemorrhoids and rectal prolapse.

●Faming Zhang conceived Transendoscopic Enteral Tubing(TET) for the frequent colonic delivery of FMT. We reported the step-up FMT strategy; Sponsored the 2nd National Conference on Intestinal Disease and Fecal Microbiota Transplantation,launched the non-profit “Chinese fmtBank Emergency Rescue Plan”, and established the first GMP laboratory system used for microbiota transplantation in the world.

●The journal Gut Microbes invited Dr. Faming Zhang to review the step-up FMT strategy; We sponsored the 3rd China Academic Conference on Integrated Bowel Disease; Published best-selling medical popular book entitled INTESTINE IN PERIL; Built GMP Laboratory for FMT in Sir Run Run Hospital, Nanjing Medical University; Invented mini-FMT and started multi-center clinical research.NATURE's annual review highlighted our report on the medical history of FMT; Dr. Faming Zhang gavea lecture at the World Life Science Conference and wrote the article entitled ``fecal microbiota transplantation system``; Dr. Xingyin Liu was selected as the distinctive medical talent in Jiangsu Province; Dr. Faming Zhang, Dr. Xingyin Liu, and Dr. Bota Cui gained fundings from the National Natural Science Foundation of China.

●Dr. Faming Zhang was awarded as the Leading Talents of Jiangsu Province; We sponsored the 2017 China Microbiota Transplantation Conference, a landmark meeting in the field of gut microbiota in China; and established China Microbiota Transplantation System. Zhi He et al. first time reported the FMT treatment strategy for Crohn's disease with inflammatory mass.Ting Zhang et al. first time reported the cost-effectiveness results of FMT for inflammatory bowel disease. Zhi He et al. reported the first FMT to cure epilepsy and registered the first clinical trial.Chinese Journal of Gastroenterology published“The Chinese fmtBank Rescue Plan”from us.

●We co-sponsored the 2018 China Gut Festival with 2500+ participants at the China National Convention Centerin Beijing. Dr. Faming Zhang lead the FMT-standardization Study Group and published a cover paper in Protein&Cell; Dr. Chuyan Long et al. reported the first research results on the technique of a novel quick transendoscopic enteral tubing in mid-gut; Dr. PanLiet al. first time reported the timing for the second FMT to maintain the long-term benefit from the first treatment for Crohn’s disease; Dr. Honggang Wang et al. first time reported that GenFMTer reduced the adverse events of FMT but did not affect the efficacy.

● We co-sponsored the 2019 China Gut Festival with5000+ participants at beijing. We reported the clinical findings, animal studies and in vitro screening between washed microbiota transplantation andmanual fecal microbiota transplantation. Professor Faming Zhang led a consensus team with 28 experts developed Nanjing Consensus on methodology of washed microbiota transplantation. More reports on WMT can be found in this website.

We first time demonstrated that WMT is safe and effective to improve intestinal symptoms and mucosal injury in patients with chronic radiation enteritis. Our latest findings indicate that it is important to understand the efficacy of WMT in Crohn’s disease as a targeted therapy, especially for abdominal pain, hematochezia, fever and diarrhea.

We published the world's first successful eradication of invasive fungal infections through FMT in Chin Med J;We first reported the value and safety of colonic TET in young children;The China Gut Festival, with a record-breaking attendance of over 6000 participants, was successfully held in May in Nanjing;Faming Zhang reported the successful use of colonic TET for decompressing intestinal perforations, avoiding surgical intervention in Endoscopy;We demonstrated the superior long-term efficacy of FMT combined with infliximab in Crohn's disease;We published the therapeutic effects and mechanisms of WMT in managing stress-related conditions;We revealed the dynamic circadian rhythms of the ileocecal region through live sampling during colonic TET;Under the leadership of Faming Zhang, the expert team at the China Gut Festival developed the anal positioning LPRA method and updated the CAES protocol.

Collaboration with Zhang Yan's team led to the first report in Environ Sci Technol, showcasing how microplastics promote the progression of IBD;A 10-year research endeavor was published in the journal ``Microb Biotechnol``, presenting the development of CMTS;The effective control of amyotrophic lateral sclerosis (ALS) by WMT was first reported in J Biomed Res;In Chin Med J, it was stated that WMT and TET are the core advancements in the global field of fecal microbiota transplantation;The first national standard for WMT in China, led by our team, was officially released and implemented;The establishment of the Human Microbiota Salon facilitated the exchange and development of microbiome medicine;The construction of a world-renowned laboratory in the field of microbiome diagnosis and treatment technology was completed;The related invention technologies entered a new stage in LBP.

Faming Zhang introduced microbiome medicine as a clinical medical discipline for the first time;The Human Microbiota Salon was inaugurated;Under the leadership of Faming Zhang, the expert group at the China Gut Festival published expert opinions on TET;The course ``Microbiome Medicine`` was offered for the first time at Nanjing Medical University;The national integrated treatment plan for malnutrition was launched.<br /> We published their achievements in Cell Metabolism and other journals;We first reported the successful relief of small intestinal obstruction through TET;Faming Zhang was approved as the chief editor of the national textbook ``Microbiome Medicine``;We published WMT for multi-center CDI across the country.

Contact us

We are happy to help if you have any query. Please contact us to find out the services we offer at:

Nanjing Medical University

Email: iidonate@163.com

Phone/wechat: (+86) 189-5176-2846

Fax: (+86) 025-5850-9931

Wechat Official Accounts: fmtBank

Address 1: 121 Nanjing Jiang Jia Yuan,Gulou, Nanjing 210011, China.

The Second Affiliated Hospital of Nanjing Medical University

Address 2: 109 Long Mian Avenue, Jiangning, Nanjing 210011, China.

Sir Run Run Hospital, Nanjing Medical University

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刘晔律师,上海市海上律师事务所合伙人,曾在同济医科大学、复旦大学上海医学院学医,后学法。
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马永慧,副教授,厦门大学医学院助理教授,英国曼彻斯特大学生命伦理学博士。
Email:yhma@xmu.edu.cn
地址:厦门大学翔安校区 医学院爱礼楼 109