中华粪菌库 |

Bowel preparation after mid-gut tubing enhanced the efficacy and compliance of magnetic resonance enterography in Crohn’s disease: a randomized controlled trial

Posted at 16:37h in News

Background: Magnetic resonance enterography (MRE) has become a routine intestinal imaging examination for Crohn’s disease (CD). Sufficient bowel preparation is fundamental for MRE. Objectives: To compare the efficacy and compliance of bowel preparation between through a mid-gut tube and oral administration for MRE in CD. Design: This...

A predictive machine-learning model for clinical decision-making in washed microbiota transplantation on ulcerative colitis

Posted at 08:57h in News

Background Machine learning based on clinical data and treatment protocols for better clinical decision-making is a current research hotspot. This study aimed to build a machine learning model on washed microbiota transplantation (WMT) for ulcerative colitis (UC), providing patients and clinicians with a new evaluation system...

Washed microbiota transplantation improved the level of serum vitamin D in ulcerative colitis

Posted at 20:15h in News

Background and Aim: Vitamin D (VD) deficiency was reported to correlate with ulcerative colitis (UC) activity, which might be closely related to gut microbiota dysbiosis. This study aims to investigate the effects of washed microbiota transplantation (WMT) on VD metabolism in UC. Methods: The serum levels...

Successful management of fecalith impaction in the distal ileum using a transendoscopic enteral tube for targeted drug delivery

Posted at 19:30h in News

In August 2024, our team first reported on the use of transendoscopic enteral tube (TET) for targeted ileal drug delivery to resolve massive fecal impaction in the small intestine in the international leading journal 《Endoscopy》. This is the third paper on TET technology published in...

Washed microbiota transplantation improves the sleep quality in patients with inflammatory bowel disease

Posted at 17:03h in News

There is scarce evidence to support the effectiveness of faecal microbiota transplantation (FMT) in improving sleep among individuals with inflammatory bowel disease (IBD). Our study aims to evaluate the effect of washed microbiota transplantation (WMT) (the new method of FMT) on the sleep of patients...

Comparison of propofol-esketamine versus propofol-sufentanil for deep sedation and analgesia in children with autism: A randomized double-blind clinical trial

Posted at 16:14h in News

Propofol sedation, routinely used for endoscopic procedures, is safe and acceptable for children. Adjuvants, such as esketamine or sufentanil, are commonly added to improve the efficacy and safety of propofol sedation. This study aimed to compare the clinical efficacy and safety of propofol-esketamine (PE) versus...

Radiation injury and gut microbiota-based treatment

Posted at 18:31h in News

The exposure to either medical sources or accidental radiation can cause varying degrees of radiation injury (RI). RI is a common disease involving multiple human body parts and organs, yet effective treatments are currently limited. Accumulating evidence suggests gut microbiota are closely associated with the...

WMT in systemic sclerosis: a case report

Posted at 18:09h in News

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by skin thickening and fibrosis, which may involve multiple organs and systems. Recent studies have indicated that patients with SSc frequently exhibit gut microbiota dysbiosis, suggesting that the gut microbiota may play a role in the...

Innovative management of intestinal obstruction with colonic transendoscopic enteral tubing

Posted at 23:28h in News

A 50-year-old man with a 15-year history of Crohn’s disease (CD) was urgently admitted due to abdominal distension, which had worsened over a week. In the preceding 3 months, he had undergone exclusive enteral nutrition. The abdominal distension persisted despite accepting symptomatic treatments such as fasting...

Comparison between washed microbiota transplantation and infliximab: Medical cost during long-term management in patients with inflammatory bowel disease

Posted at 17:27h in News

Background: Both infliximab (IFX) and fecal microbiota transplantation (FMT) have shown the efficacy for inflammatory bowel disease (IBD). However, there has no head-to-head study on the cost-value of the such treatments on IBD. This study aimed to compare the medical costs using IFX and the new...